Van de Ven Double Halts Everton's Run at New Stadium
Micky van de Ven became the first defender to score twice in a Premier League game for Spurs since Jan Vertonghen in spring 2013.
At a glance
Micky Van de Ven nods into the net two times in first half
The home side's defender has equalizer disallowed after video check
Senegalese midfielder scores third in 89th minute
This loss is the Merseyside club's initial at Hill Dickinson Stadium
The Tottenham defender scored twice as Spurs extended their winning streak on the road in the Premier League and delivered the Toffees their initial loss at their new home.
Everton were undefeated in their five previous fixtures at their new ground at the dockside location, having departed their historic home behind after 133 years at the conclusion of last season.
But Tottenham's leader the Dutchman struck twice from set-pieces in the first half to put their strong form at jeopardy, and they were failed to turn it around before the midfielder - assisted by former Toffees attacker the Brazilian - headed home a final goal to seal the victory.
Jake O'Brien thought he had levelled the scores a short while after Van de Ven's first goal, directing a powerful header past Guglielmo Vicario from an Everton corner.
Beto, meanwhile, failed to convert a number of chances, while Vicario made a series of excellent saves to ensure Tottenham went five matches on the road without defeat in the Premier League.
But the VAR stepped in, instructing Craig Pawson to review the score on the pitchside monitor and the official decided that Jack Grealish and the attacker were in offside positions and had impeded with the Tottenham goalkeeper.
The win moves the manager's side into third place in the division, a handful of points off north London rivals and leaders Arsenal.
The Merseyside club remain in 14th position and are half a dozen points clear of the relegation zone.
Spurs breakdown: Van de Ven excels in duties at each end of pitch
After a uninspiring midweek display in the Champions League against Monaco, where they managed a mere two shots on goal, Frank chose the French striker in attack instead of ex-Everton forward the Brazilian.
The new arrival was failed to make much of an impact before being substituted for Richarlison after 60 minutes on the pitch, but it emerged he wasn't needed in the final outcome.
Defender Van de Ven converted into an attacking force to be reckoned with.
Spurs' first goal came from a cleverly executed corner routine, with Rodrigo Bentancur directing the ball toward the face of goal for an unmarked Van de Ven to head home.
And Ven de Ven - filling in as captain in Cristian Romero's unavailability - added his second in first-half stoppage time as he outjumped the England keeper to nod in.
Van de Ven was just as impressive in defence, partnering well with Kevin Danso as the duo dealt superbly with the 34 crosses thrown their way by the opposition.
Toffees breakdown: Toffees lacking finishing touch
Everton's new home had been a fortress, but it seems the novelty may have worn off somewhat and fans headed to the exits after the midfielder's third for Spurs.
The break in the team's unbeaten home run won't be a massive worry for the manager, but their attacking woes are.
Beto and the other striker - the Everton's two established centre-forwards - had netted just a single goal combined before Sunday's outing.
And they were failed to add to that miserable record on a wet and gloomy evening on Merseyside.
Beto's performance was summed up when he opted to bicycle-kick a golden opportunity from near the goal, despite having room and opportunity to reposition for a more conventional attempt that would have tested Vicario.
Barry, as well, was unable to make an impact after coming on for Beto in the second half.
It was not for a lack of opportunity. Most of the home side's offensive moves came through Grealish and Ndiaye, who tirelessly whipped dangerous crosses into the Spurs penalty area.
What next for these two sides?
The Toffees: Moyes' men head to Sunderland in the Premier League on early November at 20:00 GMT.
Spurs: Spurs go to Newcastle's ground on late October for their next round Carabao Cup tie against the Magpies.